Each year, 800 people wait for an organ transplant in Sweden. The development of drugs for organ rejection has evolved over the past 60 years, which has increased the survival of patients who have undergone organ transplantation. The most common organ transplanted is the kidney, liver, lung and heart. There are more studies done on quality of life after an organ transplant, but very few studies on quality of life before organ transplantation.The aim of the study was to describe the experiences of quality of life among patients waiting for an organ transplant.A literature overview of eight articles was analyzed in both similarities and differences. The articles were published between 2002 and 2012.The result is presented in four themes, hope of life, living in uncertainty, the body fails and need for support.

Background: A life with severe chronic heart failure is debilitating, and most patients die of the disease. The possibility of having a heart from a deceased donor is often the patient's only hope of continued life. Aim: To gain a deeper insight and understanding of the patients experiences after a heart transplant. Method: Literature study with results based on 13 scientific articles. Results: Gratitude was the great common experience for the recipients of new hearts.

Inclusion body disease (IBD) affecting boas and pythons is a serious and common disease. Boas can be clinically healthy carriers, which makes control of the disease difficult. The causative agent has not yet been confidently identified, and therefore there are no serodiagnostic tests available. Today, histopathologic examination of tissue biopsies is the recommended antemortem diagnostic method, but there are several disadvantages. The objective of this study was to compare the sensitivity of two diagnostic methods ? liver biopsies and blood smears, and to evaluate ultrasoundguided needle biopsy of the liver.

Background:For patients with severe heart disease, may heart transplantation be the only opportunity for survival. Previous research highlights the importance of the nurse's role as supporters and knowledge brokers. People who has undergone heart transplant may be changed forever. Having to undergo a heart transplant can lead to that patients end up in a traumatic crisis. People's perception of herself and her perception of the world is also changing when the body is injured or suffers a disease.

Sjuksköterskan bör ha kunskap om begreppet livskvalitet för att kunna bemöta patienter som genomgått en levertransplantation, då den upplevda livskvalitén är betydelsefull för patienterna. Syftet var att beskriva livskvalitet hos patienter som genomgått en levertransplantation. Studien är genomförd som en litteraturstudie där 12 vetenskapliga artiklar har granskats. Resultatet visar att den upplevda livskvalitén hos levertransplanterade patienter är relativt god men det finns delar av livskvalitén som påverkas negativt efter levertransplantationen. Livskvalitén påverkas av fysiska, psykiska och sociala aspekter.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: BCAA supplementation in patients undergoing resection for liver cancerAuthor: Mikael Semaan and Viktor SjölingSupervisor: Fredrik BertzExaminer: Frode SlindeProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 10, 2013BackgroundLiver cancer is the fifth most common cancer worldwide and the third largest to cause death. Protein-energy malnutrition is common in patients with liver disease and they often suffer from changes in the hepatic metabolism of nutrients and other substances. There is a basis for recommending BCAA supplementation in other certain liver diseases. Given the similar clinical picture of liver cancer surgery, it is possible that supplementation of BCAA can be beneficial for these patients as well.ObjectiveThe aim was to study the scientific basis for the effect of branched chain amino acid (BCAA) supplementation in liver cancer patients. Can it improve their recovery in terms of nutritional status and albumin levels, and does it changes the duration of hospital stay, after surgery?Search strategyFive extensive searches were performed on PubMed and Cochrane after appropriate study material.

Perfluoroalkyl substances (PFASs) are ubiquitous in the environment today and they have been detected even in remote areas such as the Arctic. PFASs can be transported by the atmosphere and ocean currents but the transport mechanism is not fully understood. PFASs may be harmful to organisms due to their persistence in the environment, bio-accumulation potential and toxicity. Studies have shown that PFASs can cause adverse effects on the metabolism as well as the endocrine- and reproduction systems in organisms. In this study, PFASs were investigated in glaucous gull (Larus hyperboreus) (n=5) and black guillemot (Cepphus grylle) (n=4) from Svalbard.

 Bakgrund: Väntelistorna för de patienter som står i kö för en levertransplantation blir allt längre i alla länder runt om i världen. Väntetiden upplevs för patienterna som en psykiskt och socialt påfrestande tid eftersom det är oklart om och när ett organ som passar blir tillgängligt. Det är viktigt att sjuksköterskan antar utmaningen att möta lidandet och den lidande människan och bidra till att minska detta. Syfte: Syftet med litteraturstudien var att belysa och beskriva patienters upplevelser i väntan på en levertransplantation. Metod: Litteraturstudien bygger på totalt 10 kvalitativa och kvantitativa vetenskapliga artiklar.

En levertransplantation är ett livsförändrande ingrepp som innebär en chans till ett nytt liv för patienter med en livshotande diagnos. Ingreppet medför också stora omställningar för patienter i form av fysiska och psykiska svårigheter. Genom att få en större inblick i patienters livssituation kan sjuksköterskorna med den nyvunna kunskapen, ge en bättre anpassad vård till patienterna. Syftet med denna uppsats är att belysa patienternas upplevelser av sin livssituation efter en levertransplantation. Metoden som används är en litteratur baserad studie utifrån kvalitativa vetenskapliga artiklar, inriktat på patienters upplevelse kring levertransplantation.

Aim: To investigate the quality of life and the social life situation, with special focus on the consequenses of fear of hypoglycemia (FoH), in Islet transplanted patients.Method: 11 patients were included, four women and seven men, who have been Islet tranplanted at Uppsala University Hospital during the years 2001-2009. Two questionaires, Short Form 36 (SF-36) and the Swedish version Hypoglycemia Fear Survey (Swe-HFS) were used to investigate the quality of life, in relation to fear of hypoglycemia. Also, telephone interviews were conducted to investigate the patients social life situation in relation to FoH, after Islet transplantation and were analysed using content analysis method.Results: The mean value for quality of life was lower than that in the normal population. Three out of ten patients experienced FoH. Three predominant themes were revealed, one theme associated with pre- transplant, was ?Struggle for control of Social Life Situation? and two themes associated with post-transplant, were ?Regain power and controll of  Social Life Situation? and ?At Peace with the balance between the Present and the Future?.Conclusion: The patients experienced improved control over social life situation and quality of life in relation to FoH may been improved following islet tranplantation..

There is convincing research which shows that the enzyme alkaline phosphatase (ALP) has a central role in the mineralization of bone, more precisely that its catalytic activity is needed in the process. ALP is found on the surface of matrix vesicles where the mineral is formed. One theory about the function of the enzyme is that it binds to fibrous collagen in the bone and thereby incorporating the mineral into the bone. The purpose of this study is to establish whether ALP binds to collagen. If this is the case, more elaborate studies around this will be performed.

Mussel meal is a potential source of protein, with a good composition of amino acids, for laying hens and broiler chickens, and may replace the use of fish meal in organic poultry production. Lead and cadmium are heavy metals which occur in the environment and can be accumulated in mussels. When poultry are exposed to heavy metals, the metals are absorbed in the small intestine and distributed in the body in the form of ions, complexes or bound to proteins. In poultry, lead accumulates in bone tissue, liver and kidneys, while cadmium accumulates in liver and kidneys. Generally very low concentrations of these heavy metals occur in muscles of broilers which have been exposed to feed contaminated with cadmium or lead.

Since several lifestyle diseases are associated with obesity much research is carried out within the area. Researchers have found that oxidation of fatty acids within the body?s cells may give rise to peripheral signals which regulate food intake, but it is still unclear where such a mechanism takes place. Although much evidence suggests that it is the hepatocytes in the liver that send signals regulating food intake, some researchers have begun to question this theory. Instead they argue that the mechanism takes place within the enterocytes since they are well localised in the gut for such assignment.

Bakgrund: Levercirros är ett sjukdomstillstånd som har hög mortalitet om inte en levertransplantation genomförs. Väntelistan till transplantation är lång samtidigt som organbehovet ökar. Syfte: Syftet med studien är att beskriva patientens upplevelser och livskvalitet i väntan på en levertransplantation. Metod: En litteraturöversikt valdes där 9 vetenskapliga artiklar granskades och analyserades enligt Fribergs modell (2006). Resultat: Beskedet om att bli uppsatt på väntelista präglades av både positiva och negativa känslor; glädje, lättnad, oro samt tveksamhet.

To date, the genus Helicobacter consist of 26 different species and even more species are yet to be characterized. Helicobacter has been detected in connection with diseases in the liver and pancreas in humans and animals. Helicobacter spp. are gram negative, curved, S-shaped or spiral shaped bacteria. They are microaerophilic and have flagella that make them motile. Helicobacter, present in the gastric mucosa neutralize the gastric acid through production of urease that hydrolyses urea to ammonia and bicarbonate.